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This promotional website is managed and funded by Angelini Pharma and is intended for UK and Ireland healthcare professionals only.

Welcome to the Resources vault for ONTOZRY® (cenobamate)

A comprehensive library of resources designed to support your clinical practice and patients prescribed ONTOZRY®. All resources are available in print and digital versions. To order print copies, please email info@angelinipharma.com.

For healthcare professionals - Resources designed for your clinical practice

A guide for healthcare professionals

This guide has been developed to help you support your patients with epilepsy whose focal-onset seizures are drug resistant and have been prescribed ONTOZRY®, as well as information on how you can support your patients during treatment.

Click here to access the digital version.

Managing drug–drug interactions

Practical insights on managing drug–drug interactions with ONTOZRY® to optimise treatment outcomes in adults with focal-onset epilepsy.

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How to initiate your patients

A practical guide outlining the steps to initiate ONTOZRY® in adults with focal-onset epilepsy, including titration, dosing and co-medication.

Click here to access the digital version.

Titration guide

The titration guide provides practical, evidence-based strategies to optimise seizure control and treatment tolerability in focal-onset epilepsy.

Click here to access the digital version.

Updated NICE Technology Appraisal

NICE updated its guidance on ONTOZRY® in May 2025 – read the recommendations in this summary leaflet.

Click here to access the digital version.

For patients – Resources designed for your patients prescribed ONTOZRY®

Introduction guide

This guide is for people who have been prescribed ONTOZRY® as an add-on to their existing epilepsy medicine. It has been designed to support your patients during treatment and answer frequently asked questions.

Click here to access the digital version.

Titration diary

The ONTOZRY® titration diary is a practical tool to help your patients through the start of treatment by tracking doses, seizures and side effects.

Click here to access the digital version.

Indications

United Kingdom: ONTOZRY® (cenobamate) is indicated for the adjunctive treatment of focal–onset seizures with or without secondary generalisation in adult patients with epilepsy who have not been adequately controlled despite treatment with at least 2 anti–epileptic medicinal products.1

Republic of Ireland: ONTOZRY® (cenobamate) is indicated for the adjunctive treatment of focal–onset seizures with or without secondary generalisation in adult patients with epilepsy who have not been adequately controlled despite a history of treatment with at least 2 anti–epileptic medicinal products.1

1. ONTOZRY® Summary of Product Characteristics. United Kingdom and European Union.

MAT-UKI-0222-P | September 2025